Anti-CD80 antibody [MEM-233] (STJ16100188)

SKU:
STJ16100188-01

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Host: Mouse
Applications: FC/IP
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CD80 is suitable for use in Flow Cytometry and Immunoprecipitation research applications.
Clonality: Monoclonal
Clone ID: MEM-233
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration: 1 mg/mL
Storage Instruction: Store at 2-8°C upon receipt.
Gene Symbol: CD80
Gene ID: 941
Uniprot ID: CD80_HUMAN
Immunogen: Extracellular domain of human CD80 fused to human IgG1 (Fc)
Tissue Specificity Expressed on activated B-cells, macrophages and dendritic cells.
Function Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. (Microbial infection) Acts as a receptor for adenovirus subgroup B.
Protein Name T-Lymphocyte Activation Antigen Cd80
Activation B7-1 Antigen
Bb1
Ctla-4 Counter-Receptor B7.1
B7
Cd Antigen Cd80
Database Links Reactome: R-HSA-1257604
Reactome: R-HSA-2219530
Reactome: R-HSA-389356
Reactome: R-HSA-389357
Reactome: R-HSA-389359
Reactome: R-HSA-389513
Reactome: R-HSA-6783783
Reactome: R-HSA-6811558
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-T-Lymphocyte Activation Antigen Cd80 antibody
Anti-Activation B7-1 Antigen antibody
Anti-Bb1 antibody
Anti-Ctla-4 Counter-Receptor B7.1 antibody
Anti-B7 antibody
Anti-Cd Antigen Cd80 antibody
Anti-CD80 antibody
Anti-CD28LG antibody
Anti-CD28LG1 antibody
Anti-LAB7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance