Anti-CD8 antibody [C8/144B] (STJ16100344)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
STJ16100344
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General Information

Short DescriptionMouse monoclonal anti-CD8 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC-P
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDC8/144B
IsotypeIgG1k
ConjugationUnconjugated
Dilution RangeIHC 1: 25 – 1:100
FormulationTris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Storage InstructionStore at 2-8°C for up to 1-year, upon receipt.

Target Information

Additional Info

Background The CD8 (cluster of differentiation 8) antigen is a cell surface glycoprotein made up of two subunits alpha and beta.1 Anti-CD8 is a T-cell marker for the detection of cytotoxic/suppressor lymphocytes. CD8 is also detected on NK cells, some thymocytes, some null cells and bone marrow cells. This antibody, along with other markers, can be used to distinguish between reactive and neoplastic Tcells.3 CD8 expression has been found to be negative in Mycosis Fungoides. Rarely does anti-CD8 label non-hematolymphoid neoplasms.

Information sourced from Uniprot.org

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