Anti-CD73 antibody [M064] (STJA0005337)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenClone (M064) was generated from a proprietary antigen related to the mature form of CD73 expressed in the NCI-H1299 lung cancer cell line.
General Information
| Short Description | Mouse monoclonal antibody anti-CD73/NT5E is suitable for use in Western Blot and Immunoprecipitation research applications. |
| Applications | WB/IP |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | M064 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Protein G Purified |
| Dilution Range | WB 1:500IP 1:50 |
| Formulation | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NT5E |
| Gene ID | 4907 |
| Uniprot ID | 5NTD_HUMAN |
| Immunogen | Clone (M064) was generated from a proprietary antigen related to the mature form of CD73 expressed in the NCI-H1299 lung cancer cell line. |
| Specificity | Clone M064 mouse monoclonal antibody detects a 65 kDa* protein on SDSPAGE Native" immunoblots of human H1299, H1915, and MDA-MB-231 carcinomas. This antibody weakly detects denatured CD73. The antibody works for native western blot, immunoprecipitati |
Additional Info
| Function | Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate. Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms. Other substrates include IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN. |
| Protein Name | 5'-Nucleotidase5'-Nt 5'-DeoxynucleotidaseEcto-5'-NucleotidaseImp-Specific 5'-NucleotidaseThymidylate 5'-PhosphataseCd Antigen Cd73 |
| Database Links | Reactome: R-HSA-196807Reactome: R-HSA-73621Reactome: R-HSA-74259Reactome: R-HSA-9660826 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-5'-Nucleotidase antibodyAnti-5'-Nt antibodyAnti-5'-Deoxynucleotidase antibodyAnti-Ecto-5'-Nucleotidase antibodyAnti-Imp-Specific 5'-Nucleotidase antibodyAnti-Thymidylate 5'-Phosphatase antibodyAnti-Cd Antigen Cd73 antibodyAnti-NT5E antibodyAnti-NT5 antibodyAnti-NTE antibody |
Information sourced from Uniprot.org