Anti-CD71 antibody [MEM-75] {FITC} (STJ16100073)

SKU:

STJ16100073-100

£521.50

General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Mouse
Applications:	FC
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Mouse monoclonal antibody anti-CD71 is suitable for use in Flow Cytometry research applications.

Clonality:	Monoclonal
Clone ID:	MEM-75
Conjugation:	FITC
Isotype:	IgG1
Formulation:	Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Dilution Range:	FC using 20 Mu l reagent/100 Mu l of whole blood or 106 cells ina suspension.
Storage Instruction:	Store at 2-8°C upon receipt.

Immunogen:

NALM-6 human pre-B cell line

Background

CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions) , CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH. CD71 is also involved in uptake of non-transferrin bound iron.

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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