Anti-CD71 antibody [IHC071] (STJA0042034)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal anti-CD71 for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-p |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | IHC071 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Dilution Range | 1:50-1:200 |
| Formulation | Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1 year. Do not freeze. |
Target Information
| Specificity | Tested and validated on bone marrow tissue. |
Additional Info
| Background | Cluster on Differentiation 71 (CD71) , also known as Transferrin Receptor Protein 1 (TfR1) or the transferrin receptor, is a cell surface proliferation marker that is involved in the cellular uptake on iron. CD71 is most highly expressed in early erythroid precursors and is fully absent from mature erythrocytes; CD71 is therefore highly useful as a marker for erythroid components within bone marrow biopsy specimens, without interference from mature erythrocytes. CD71 expression has been indicated in invasive breast carcinoma with acquired resistance to tamoxifen, and has been linked to poor prognosis in ER+/luminal-like breast cancer. Anti-CD71 is used in the determination on erythroid leukemia, benign erythroid proliferative disorders, and myelodysplastic syndrome. |
Information sourced from Uniprot.org