Anti-CD71 antibody [10F11] (STJ16101812)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2b
ImmunogenProkaryotic recombinant protein corresponding to a region of the N-terminal intracellular domain of the human CD71 molecule.
General Information
| Short Description | Mouse monoclonal anti-CD71 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 10F11 |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Concentration | >=42 mg/L |
| Dilution Range | IHC-P 1:80 |
| Formulation | Tissue culture supernatant with sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | Prokaryotic recombinant protein corresponding to a region of the N-terminal intracellular domain of the human CD71 molecule. |
Additional Info
| Background | The CD71 molecule is a type II membrane glycoprotein with a molecular weight of approximately 180 kD. It is known as the transferrin receptor and is composed of two disulfide-bonded 90 kD subunits. The CD71 molecule plays a critical role in cell proliferation by controlling the supply of iron, an essential component for many metabolic pathways, through the binding and endocytosis of transferrin, the major iron-carrying protein. CD71 protein is reported to be expressed on activated B and T cells, macrophages, proliferating cells and metabolically active cells, for example, neurons. |
Information sourced from Uniprot.org