Anti-CD71 antibody [10F11] (STJ16101812)

SKU:
STJ16101812-1

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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CD71 is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: 10F11
Conjugation: Unconjugated
Isotype: IgG2b
Formulation: Tissue culture supernatant with sodium azide
Concentration: >=42 mg/L
Dilution Range: IHC-P 1:80
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Prokaryotic recombinant protein corresponding to a region of the N-terminal intracellular domain of the human CD71 molecule.
Background The CD71 molecule is a type II membrane glycoprotein with a molecular weight of approximately 180 kD. It is known as the transferrin receptor and is composed of two disulfide-bonded 90 kD subunits. The CD71 molecule plays a critical role in cell proliferation by controlling the supply of iron, an essential component for many metabolic pathways, through the binding and endocytosis of transferrin, the major iron-carrying protein. CD71 protein is reported to be expressed on activated B and T cells, macrophages, proliferating cells and metabolically active cells, for example, neurons.

Information sourced from Uniprot.org

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