Anti-CD7 antibody (141-240) [S1MR] (STJ11102491)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal CD7 (141-240) antibody for use in WB, IHC-P and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S1MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:2000-1:10000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CD7 |
| Gene ID | 924 |
| Uniprot ID | CD7_HUMAN |
| Immunogen Region | 141-240 |
| Immunogen Sequence | RCSDAPPRASALPAPPTGSA LPDPQTASALPDPPAASALP AALAVISFLLGLGLGVACVL ARTQIKKLCSWRDKNSAACV VYEDMSHSRCNTLSSPNQYQ |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 141-240 of human CD7 (P09564). |
Additional Info
| Tissue Specificity | Expressed on T-cells and natural killer (NK) cells and their precursors. |
| Function | Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1. In turn, mediates the production of cytokines such as IL-2. On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels. |
| Protein Name | T-Cell Antigen Cd7Gp40T-Cell Leukemia AntigenT-Cell Surface Antigen Leu-9Tp41Cd Antigen Cd7 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-T-Cell Antigen Cd7 antibodyAnti-Gp40 antibodyAnti-T-Cell Leukemia Antigen antibodyAnti-T-Cell Surface Antigen Leu-9 antibodyAnti-Tp41 antibodyAnti-Cd Antigen Cd7 antibodyAnti-CD7 antibody |
Information sourced from Uniprot.org