Anti-CD7 antibody (132-146) (STJ72678)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-CD7 (132-146) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 37kDa band observed in Human Thymus lysates (calculated MW of 25.4kDa according to NP_006128.1). We do note that CD7 is a glycoprotein which makes a higher size band to be expec |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | CD7 |
| Gene ID | 924 |
| Uniprot ID | CD7_HUMAN |
| Accession Number | NP_006128.1 |
| Immunogen Region | 132-146 |
| Immunogen Sequence | TEEQSQGWHRCSDAP |
| Specificity | The immunizing peptide corresponds to a part of the extracellular domain. |
Additional Info
| Function | Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1. In turn, mediates the production of cytokines such as IL-2. On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels. |
| Protein Name | T-Cell Antigen Cd7Gp40T-Cell Leukemia AntigenT-Cell Surface Antigen Leu-9Tp41Cd Antigen Cd7 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-T-Cell Antigen Cd7 antibodyAnti-Gp40 antibodyAnti-T-Cell Leukemia Antigen antibodyAnti-T-Cell Surface Antigen Leu-9 antibodyAnti-Tp41 antibodyAnti-Cd Antigen Cd7 antibodyAnti-CD7 antibody |
Information sourced from Uniprot.org