| Host: |
Mouse |
| Applications: |
IHC/IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-CD68 is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
SM0477 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1k |
| Formulation: |
PBS with 0.15% ProClin300, 100 Mu g/mL BSA and 50% glycerol. |
| Purification: |
Affinity purification |
| Dilution Range: |
IHC/IF (H) 1:500-1:1000 |
| Storage Instruction: |
Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: |
CD68 |
| Gene ID: |
968 |
| Uniprot ID: |
CD68_HUMAN |
| Immunogen: |
Recombinant protein corresponding to Human CD68 |
| Post Translational Modifications | N- and O-glycosylated. |
| Function | Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. |
| Protein Name | MacrosialinGp110Cd Antigen Cd68 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Isoform Short: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Long: Endosome MembraneLysosome Membrane |
| Alternative Antibody Names | Anti-Macrosialin antibodyAnti-Gp110 antibodyAnti-Cd Antigen Cd68 antibodyAnti-CD68 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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