Anti-CD68 antibody (240-290) {FITC} (STJ500482)

SKU:
STJ500482-100

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Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CD68 (240-290) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: FITC
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5-1.5 µg/µl
Dilution Range: WB: 1:2, 500-1:5, 000
ELISA: 1:50, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Cd68
Gene ID: 12514
Uniprot ID: CD68_MOUSE
Immunogen Region: 240-290
Immunogen: Synthetic peptide taken within amino acid region 240-290 on mouse CD68/Macrosialin protein.
Tissue Specificity Expressed in tissue macrophages and to a lesser extent in dendritic cells.
Post Translational Modifications N- and O-glycosylated.
Function Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Protein Name Macrosialin
Cd Antigen Cd68
Database Links Reactome: R-MMU-6798695
Cellular Localisation Isoform Long: Endosome Membrane
Single-Pass Type I Membrane Protein
Lysosome Membrane
Isoform Short: Cell Membrane
Alternative Antibody Names Anti-Macrosialin antibody
Anti-Cd Antigen Cd68 antibody
Anti-Cd68 antibody

Information sourced from Uniprot.org

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