Anti-CD68 antibody (240-290) {Biotin} (STJ500481)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 240-290 on mouse CD68/Macrosialin protein.
STJ500481-100
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General Information

Short DescriptionRabbit polyclonal antibody anti-CD68 (240-290) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
ApplicationsELISA/IP/WB
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationBiotin
Concentration0.5-1.5 ยตg/ยตl
PurificationAffinity Purified
Dilution RangeWB: 1:2, 500-1:5, 000
ELISA: 1:50, 000
IP: 1:200
FormulationContains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage InstructionStore at-20ยฐC for long term storage. Avoid freeze-thaw cycles.

Target Information

Gene SymbolCd68
Gene ID12514
Uniprot IDCD68_MOUSE
ImmunogenSynthetic peptide taken within amino acid region 240-290 on mouse CD68/Macrosialin protein.
Immunogen Region240-290

Additional Info

Tissue Specificity Expressed in tissue macrophages and to a lesser extent in dendritic cells.
Post Translational Modifications N- and O-glycosylated.
Function Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Protein Name Macrosialin
Cd Antigen Cd68
Database Links Reactome: R-MMU-6798695
Cellular Localisation Isoform Long: Endosome Membrane
Single-Pass Type I Membrane Protein
Lysosome Membrane
Isoform Short: Cell Membrane
Alternative Antibody Names Anti-Macrosialin antibody
Anti-Cd Antigen Cd68 antibody
Anti-Cd68 antibody

Information sourced from Uniprot.org

Citations

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