Anti-CD66c/d antibody (31-80 aa) (STJ97289)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CEACAM3/CEACAM6 at the amino acid range 31-80
General Information
| Short Description | Rabbit polyclonal anti-Carcinoembryonic antigen-related cell adhesion molecule 3 and Carcinoembryonic antigen-related cell adhesion molecule 6 (31-80 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recomm |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CEACAM6CEACAM3 |
| Gene ID | 46801084 |
| Uniprot ID | CEAM6_HUMANCEAM3_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human CEACAM3/CEACAM6 at the amino acid range 31-80 |
| Immunogen Region | 31-80 aa |
| Specificity | CD66c/d Polyclonal Antibody detects endogenous levels of CD66c/d protein. |
Additional Info
| Post Translational Modifications | Tyrosine-phosphorylated in response to microbial binding. Tyr-230 and Tyr-241 are both required for phosphorylation to be detected. |
| Function | Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis. |
| Protein Name | Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3Carcinoembryonic Antigen Cgm1Cd Antigen Cd66d |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 antibodyAnti-Carcinoembryonic Antigen Cgm1 antibodyAnti-Cd Antigen Cd66d antibodyAnti-CEACAM3 antibodyAnti-CD66D antibodyAnti-CGM1 antibody |
Information sourced from Uniprot.org