Anti-CD64/FCGR1A antibody (16-292aa) [AT37F7] (STJA0041704)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2bk
ImmunogenRecombinant human FCGR1A (16-292aa) purified from E.coli
General Information
| Short Description | Mouse monoclonal anti-CD64/FCGR1A (16-292aa) for use in ELISA, WB, ICC, IF and FACS in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF/FACS |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT37F7 |
| Isotype | IgG2bk |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FCGR1A |
| Gene ID | 2209 |
| Uniprot ID | FCGR1_HUMAN |
| Accession Number | NP_000557 |
| Immunogen | Recombinant human FCGR1A (16-292aa) purified from E.coli |
| Immunogen Region | 16-292aa |
Additional Info
| Tissue Specificity | Monocyte/macrophage specific. |
| Post Translational Modifications | Phosphorylated on serine residues. |
| Function | High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells. |
| Protein Name | High Affinity Immunoglobulin Gamma Fc Receptor IIgg Fc Receptor IFc-Gamma RiFcriFc-Gamma RiaFcgammariaCd Antigen Cd64 |
| Database Links | Reactome: R-HSA-1236978Reactome: R-HSA-198933Reactome: R-HSA-2029481Reactome: R-HSA-2029482Reactome: R-HSA-2029485Reactome: R-HSA-877300Reactome: R-HSA-9664323 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinStabilized At The Cell Membrane Through Interaction With Fcer1g |
| Alternative Antibody Names | Anti-High Affinity Immunoglobulin Gamma Fc Receptor I antibodyAnti-Igg Fc Receptor I antibodyAnti-Fc-Gamma Ri antibodyAnti-Fcri antibodyAnti-Fc-Gamma Ria antibodyAnti-Fcgammaria antibodyAnti-Cd Antigen Cd64 antibodyAnti-FCGR1A antibodyAnti-FCG1 antibodyAnti-FCGR1 antibodyAnti-IGFR1 antibody |
Information sourced from Uniprot.org