Anti-CD57 antibody [HI57a] {PE/Cyanine 7} (STJA0016597)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationPE/Cyanine 7
IsotypeIgMk
General Information
| Short Description | Mouse monoclonal anti-Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | HI57a |
| Isotype | IgMk |
| Conjugation | PE/Cyanine 7 |
| Concentration | 5 Mu L/Tests |
| Purification | Affinity purified |
| Formulation | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage Instruction | Store between 2-8Β°C and protecting from prolonged exposure to light. Do not freeze this product. |
Target Information
| Gene Symbol | B3GAT1 |
| Gene ID | 27087 |
| Uniprot ID | B3GA1_HUMAN |
Additional Info
| Tissue Specificity | Mainly expressed in the brain. |
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
| Function | Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. |
| Protein Name | Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1Beta-1 -3-Glucuronyltransferase 1Glucuronosyltransferase PGlcat-PUdp-Glcua -Glycoprotein Beta-1 -3-GlucuronyltransferaseGlcuat-P |
| Database Links | Reactome: R-HSA-1971475 |
| Cellular Localisation | Isoform 1: Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinSecretedIsoform 2: Golgi Apparatus MembraneEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 antibodyAnti-Beta-1 -3-Glucuronyltransferase 1 antibodyAnti-Glucuronosyltransferase P antibodyAnti-Glcat-P antibodyAnti-Udp-Glcua -Glycoprotein Beta-1 -3-Glucuronyltransferase antibodyAnti-Glcuat-P antibodyAnti-B3GAT1 antibodyAnti-GLCATP antibody |
Information sourced from Uniprot.org