Anti-CD55 antibody {PE} (STJ11109024)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationPE
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal CD55 antibody for use in FC in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | PE |
| Purification | Affinity purification |
| Dilution Range | FC, 5 Mu l per 10^6 cells in 100 Mu l volume |
| Formulation | PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3. |
| Storage Instruction | Store at 4°C for up to 1 year from the date of receipt. Do not freeze. |
Target Information
| Gene Symbol | Cd55 |
| Gene ID | 13136 |
| Uniprot ID | DAF1_MOUSE |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Tissue Specificity | Brain, secretory epithelia, skeletal muscle, liver, testes, thymus, spleen and lymph node. |
| Function | This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage. |
| Protein Name | Complement Decay-Accelerating Factor - Gpi-AnchoredDaf-GpiCd Antigen Cd55 |
| Database Links | Reactome: R-MMU-373080Reactome: -MMU-6798695Reactome: -MMU-6807878Reactome: -MMU-977606 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Complement Decay-Accelerating Factor - Gpi-Anchored antibodyAnti-Daf-Gpi antibodyAnti-Cd Antigen Cd55 antibodyAnti-Cd55 antibodyAnti-Cd55a antibodyAnti-Daf antibodyAnti-Daf1 antibody |
Information sourced from Uniprot.org