Anti-CD55 antibody [HI55a] {FITC} (STJA0016263)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationFITC
IsotypeIgG2ak
STJA0016263
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General Information

Short DescriptionMouse monoclonal anti-Neural Cell Adhesion Molecule 1 for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsFC
HostMouse
ReactivityHuman
NoteFOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDHI55a
IsotypeIgG2ak
ConjugationFITC
Concentration5 Mu L/Tests
PurificationAffinity purified
FormulationPhosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage InstructionStore between 2-8Β°C and protecting from prolonged exposure to light. Do not freeze this product.

Target Information

Gene SymbolNCAM1
Gene ID4684
Uniprot IDNCAM1_HUMAN

Additional Info

Post Translational Modifications Polysialylated at Asn-459 and Asn-488 by ST8SIA2 and ST8SIA4. Polysialylation modulates cell interactions by confering both attractive and repulsive properties that are highly regulated by ST8SIA2 and ST8SIA4. Polysialylation is formed on a-2,3-linked sialic acid of core glycans.
Function This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. (Microbial infection) Acts as a receptor for rabies virus. (Microbial infection) Acts as a receptor for Zika virus.
Protein Name Neural Cell Adhesion Molecule 1
N-Cam-1
Ncam-1
Cd Antigen Cd56
Database Links Reactome: R-HSA-3000178
Reactome: R-HSA-375165
Reactome: R-HSA-419037
Reactome: R-HSA-445144
Reactome: R-HSA-5673001
Reactome: R-HSA-877300
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Cell Membrane
Isoform 3: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Isoform 4: Cell Membrane
Isoform 5: Secreted
Isoform 6: Secreted
Alternative Antibody Names Anti-Neural Cell Adhesion Molecule 1 antibody
Anti-N-Cam-1 antibody
Anti-Ncam-1 antibody
Anti-Cd Antigen Cd56 antibody
Anti-NCAM1 antibody
Anti-NCAM antibody

Information sourced from Uniprot.org

Citations

Product Review