Anti-CD48 antibody [EBS-CD-030] (STJ16101882)

SKU:
STJ16101882

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Host: Mouse
Applications: FC/IF/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CD48 is suitable for use in Flow Cytometry, Immunofluorescence and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: EBS-CD-030
Conjugation: Unconjugated
Isotype: IgG2ak
Formulation: PBS with 0.02% Sodium Azide.
Purification: Affinity purified from tissue culture.
Concentration: Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Dilution Range: Flow cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Immunofluorescence (0, 5-1, 0 µg/ml). Immunohistology (1-2 µg/ml for 30 min at RT; an appropriate antigen retrieval method for staining of formalin-fixed tissues has not been established to date
Storage Instruction: Store for up to 1 year at 2-8°C upon receipt.
Gene Symbol: CD48
Gene ID: 962
Uniprot ID: CD48_HUMAN
Immunogen: A BALB/c mouse was immunized with human PBL. Fusion partner: NS-1.
Function Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including 2B4/CD244 or CD2 to regulate immune cell function and activation. Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex. In turn, promotes LCK phosphorylation and subsequent activation. Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells.
Protein Name Cd48 Antigen
B-Lymphocyte Activation Marker Blast-1
Bcm1 Surface Antigen
Leukocyte Antigen Mem-102
Slam Family Member 2
Slamf2
Signaling Lymphocytic Activation Molecule 2
Tct.1
Cd Antigen Cd48
Database Links Reactome: R-HSA-202733
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Alternative Antibody Names Anti-Cd48 Antigen antibody
Anti-B-Lymphocyte Activation Marker Blast-1 antibody
Anti-Bcm1 Surface Antigen antibody
Anti-Leukocyte Antigen Mem-102 antibody
Anti-Slam Family Member 2 antibody
Anti-Slamf2 antibody
Anti-Signaling Lymphocytic Activation Molecule 2 antibody
Anti-Tct.1 antibody
Anti-Cd Antigen Cd48 antibody
Anti-CD48 antibody
Anti-BCM1 antibody
Anti-BLAST1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance