• Anti-CD48 antibody [156-4H9] {APC} (STJA0002661)

Anti-CD48 antibody [156-4H9] {APC} (STJA0002661)

SKU:
STJA0002661

Current Stock:
Host: Mouse
Applications: FC
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CD48 antigen is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: 156-4H9
Conjugation: APC
Isotype: IgG1k
Formulation: PBS with 0.05% Proclin300, 1% BSA
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: CD48
Gene ID: 962
Uniprot ID: CD48_HUMAN
Tissue Specificity Widely expressed on all hematopoietic cells.
Function Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including 2B4/CD244 or CD2 to regulate immune cell function and activation. Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex. In turn, promotes LCK phosphorylation and subsequent activation. Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells.
Protein Name Cd48 Antigen
B-Lymphocyte Activation Marker Blast-1
Bcm1 Surface Antigen
Leukocyte Antigen Mem-102
Slam Family Member 2
Slamf2
Signaling Lymphocytic Activation Molecule 2
Tct.1
Cd Antigen Cd48
Database Links Reactome: R-HSA-202733
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Alternative Antibody Names Anti-Cd48 Antigen antibody
Anti-B-Lymphocyte Activation Marker Blast-1 antibody
Anti-Bcm1 Surface Antigen antibody
Anti-Leukocyte Antigen Mem-102 antibody
Anti-Slam Family Member 2 antibody
Anti-Slamf2 antibody
Anti-Signaling Lymphocytic Activation Molecule 2 antibody
Anti-Tct.1 antibody
Anti-Cd Antigen Cd48 antibody
Anti-CD48 antibody
Anti-BCM1 antibody
Anti-BLAST1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance