• Anti-CD45RA antibody [MEM-56] (STJ16100065)

Anti-CD45RA antibody [MEM-56] (STJ16100065)

SKU:
STJ16100065-01

$531.23
Shipping:
Free Shipping
Current Stock:
Host: Mouse
Applications: FC/IP/WB/IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CD45RA is suitable for use in Flow Cytometry, Immunoprecipitation, Western Blot and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: MEM-56
Conjugation: Unconjugated
Isotype: IgG2b
Formulation: Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration: 1 mg/mL
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Human thymocytes and T lymphocytes.
Background CD45RA is a high molecular weight isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RA is expressed e.g. on naïve T cells and normal plasma cells.

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance