Anti-CD42d antibody (17-477 aa) (STJ11107110)

Name: Anti-CD42d antibody (17-477 aa) (STJ11107110)
SKU: STJ11107110
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11107110

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Short Description	Rabbit polyclonal CD42d (17-477 aa) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	GP5
Gene ID	2814
Uniprot ID	GPV_HUMAN
Immunogen Region	17-477 aa
Immunogen Sequence	QPFPCPPACKCVFRDAAQCS GGDVARISALGLPTNLTHIL LFGMGRGVLQSQSFSGMTVL QRLMISDSHISAVAPGTFSD LIKLKTLRLSRNKITHLPGA LLDKMVLLEQLFLDHNALRG IDQNMFQKLVNLQELALNQN QLDFLPASLFTNLENLKLLD LSGNNLTHLPKGLLGAQAKL ERLLLHSNRLVSLDSGLLNS LGALTELQFHRNHIRSIAPG AFDRLPNLSSLTLSRNHLA
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 17-477 of human CD42d (NP_004479.1).

Tissue Specificity	Platelets and megakaryocytes.
Post Translational Modifications	The N-terminus is blocked.
Function	The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.
Protein Name	Platelet Glycoprotein V Gpv Glycoprotein 5 Cd Antigen Cd42d
Database Links	Reactome: R-HSA-140837 Reactome: R-HSA-430116 Reactome: R-HSA-75892 Reactome: R-HSA-76009 Reactome: R-HSA-9673221 Reactome: R-HSA-9845620 Reactome: R-HSA-9846298
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative Antibody Names	Anti-Platelet Glycoprotein V antibody Anti-Gpv antibody Anti-Glycoprotein 5 antibody Anti-Cd Antigen Cd42d antibody Anti-GP5 antibody

Information sourced from Uniprot.org