• Anti-CD41/Itga2b antibody [MWReg30] {APC} (STJA0002017)

Anti-CD41/Itga2b antibody [MWReg30] {APC} (STJA0002017)

SKU:
STJA0002017

Current Stock:
Host: Rat
Applications: FC
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Rat monoclonal antibody anti-Integrin alpha-IIb is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: MWReg30
Conjugation: APC
Isotype: IgG1k
Formulation: PBS with 0.05% Proclin300, 1% BSA
Concentration: 0.2 mg/mL
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: Itga2b
Gene ID: 16399
Uniprot ID: ITA2B_MOUSE
Function Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Protein Name Integrin Alpha-Iib
Gpalpha Iib
Gpiib
Platelet Membrane Glycoprotein Iib
Cd Antigen Cd41 Cleaved Into - Integrin Alpha-Iib Heavy Chain - Integrin Alpha-Iib Light Chain
Database Links Reactome: R-MMU-114608
Reactome: -MMU-216083
Reactome: -MMU-3000178
Reactome: -MMU-354192
Reactome: -MMU-354194
Reactome: -MMU-372708
Reactome: -MMU-445144
Reactome: -MMU-5674135
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Integrin Alpha-Iib antibody
Anti-Gpalpha Iib antibody
Anti-Gpiib antibody
Anti-Platelet Membrane Glycoprotein Iib antibody
Anti-Cd Antigen Cd41 Cleaved Into - Integrin Alpha-Iib Heavy Chain - Integrin Alpha-Iib Light Chain antibody
Anti-Itga2b antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance