![Anti-CD40 antibody [LOB7/6] (STJ16100844)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149561/346878/STJ16100844_1__82158.1681999039.jpg?c=1 "Anti-CD40 antibody [LOB7/6] (STJ16100844)")
![Anti-CD40 antibody [LOB7/6] (STJ16100844)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149561/346878/STJ16100844_1__82158.1681999039.jpg?c=1 "Anti-CD40 antibody [LOB7/6] (STJ16100844)")
Anti-CD40 antibody [LOB7/6] (STJ16100844)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenCD40 Ig (Fc) fusion protein containing the EC region of human CD40 and Fc region of human IgG.
General Information
| Short Description | Mouse monoclonal anti-CD40 for use in IHC-P, FC, IHC-F and IP in Human and Dog samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/FC/IHC-F/IP |
| Host | Mouse |
| Reactivity | Human/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | LOB7/6 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1.0 mg/mL |
| Formulation | TBS |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | CD40 |
| Gene ID | 958 |
| Uniprot ID | TNR5_HUMAN |
| Immunogen | CD40 Ig (Fc) fusion protein containing the EC region of human CD40 and Fc region of human IgG. |
Additional Info
| Tissue Specificity | B-cells and in primary carcinomas. |
| Function | Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 5B-Cell Surface Antigen Cd40Bp50Cd40l ReceptorCdw40Cd Antigen Cd40 |
| Database Links | Reactome: R-HSA-198933 P25942-1Reactome: R-HSA-5668541 P25942-1Reactome: R-HSA-5676594 P25942-1 |
| Cellular Localisation | Isoform I: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Ii: Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 5 antibodyAnti-B-Cell Surface Antigen Cd40 antibodyAnti-Bp50 antibodyAnti-Cd40l Receptor antibodyAnti-Cdw40 antibodyAnti-Cd Antigen Cd40 antibodyAnti-CD40 antibodyAnti-TNFRSF5 antibody |
Information sourced from Uniprot.org