Anti-CD40 antibody [9G10] (STJ97928)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant fragment of CD40 expressed in E. Coli.
General Information
| Short Description | Mouse monoclonal anti-Tumor necrosis factor receptor superfamily member 5 for use in IF and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 9G10 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity purification |
| Dilution Range | IF 1:200-1:1000ELISA 1:10000 |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CD40 |
| Gene ID | 958 |
| Uniprot ID | TNR5_HUMAN |
| Immunogen | Purified recombinant fragment of CD40 expressed in E. Coli. |
| Specificity | CD40 Monoclonal Antibody detects endogenous levels of CD40 protein. |
Additional Info
| Function | Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 5B-Cell Surface Antigen Cd40Bp50Cd40l ReceptorCdw40Cd Antigen Cd40 |
| Database Links | Reactome: R-HSA-198933 P25942-1Reactome: R-HSA-5668541 P25942-1Reactome: R-HSA-5676594 P25942-1 |
| Cellular Localisation | Isoform I: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Ii: Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 5 antibodyAnti-B-Cell Surface Antigen Cd40 antibodyAnti-Bp50 antibodyAnti-Cd40l Receptor antibodyAnti-Cdw40 antibodyAnti-Cd Antigen Cd40 antibodyAnti-CD40 antibodyAnti-TNFRSF5 antibody |
Information sourced from Uniprot.org