![Anti-CD40 antibody [3A8] {PE} (STJA0002621)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/148405/293007/STJA0002621_1__98377.1631207088.jpg?c=1 "Anti-CD40 antibody [3A8] {PE} (STJA0002621)")
![Anti-CD40 antibody [3A8] {PE} (STJA0002621)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/148405/293007/STJA0002621_1__98377.1631207088.jpg?c=1 "Anti-CD40 antibody [3A8] {PE} (STJA0002621)")
Anti-CD40 antibody [3A8] {PE} (STJA0002621)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationPE
IsotypeIgG2ak
General Information
| Short Description | Mouse monoclonal anti-Tumor necrosis factor receptor superfamily member 5 for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 3A8 |
| Isotype | IgG2ak |
| Conjugation | PE |
| Concentration | 5 Mu L/Test |
| Formulation | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage Instruction | Store between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
Target Information
| Gene Symbol | CD40 |
| Gene ID | 958 |
| Uniprot ID | TNR5_HUMAN |
Additional Info
| Tissue Specificity | B-cells and in primary carcinomas. |
| Function | Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 5B-Cell Surface Antigen Cd40Bp50Cd40l ReceptorCdw40Cd Antigen Cd40 |
| Database Links | Reactome: R-HSA-198933 P25942-1Reactome: R-HSA-5668541 P25942-1Reactome: R-HSA-5676594 P25942-1 |
| Cellular Localisation | Isoform I: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Ii: Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 5 antibodyAnti-B-Cell Surface Antigen Cd40 antibodyAnti-Bp50 antibodyAnti-Cd40l Receptor antibodyAnti-Cdw40 antibodyAnti-Cd Antigen Cd40 antibodyAnti-CD40 antibodyAnti-TNFRSF5 antibody |
Information sourced from Uniprot.org