Anti-CD3EAP antibody (Internal) (STJ73099)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-CD3EAP (Internal) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Preliminary experiments in nuclear lysates of cell lines HeLa, Jurkat and A431 gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate a |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | POLR1G |
| Gene ID | 10849 |
| Uniprot ID | RPA34_HUMAN |
| Accession Number | NP_036231.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | PEDKTVKQEQINTEP |
Additional Info
| Function | Component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase which synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates. Involved in UBTF-activated transcription, presumably at a step following PIC formation. Isoform 2: Has been described as a component of preformed T-cell receptor (TCR) complex. |
| Protein Name | Dna-Directed Rna Polymerase I Subunit Rpa34A34.5Antisense To Ercc-1 ProteinAse-1Cd3-Epsilon-Associated ProteinCd3e-Associated ProteinDna-Directed Rna Polymerase I Subunit GRna Polymerase I-Associated Factor Paf49 |
| Database Links | Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-73762Reactome: R-HSA-73772Reactome: R-HSA-73863 |
| Cellular Localisation | NucleusNucleolusChromosomeFound At The Fibrillar Centers Of The Nucleolus In Interphase And During Cell Division It Is Localized To The Nucleolus Organizer Regions Of The Chromosomes |
| Alternative Antibody Names | Anti-Dna-Directed Rna Polymerase I Subunit Rpa34 antibodyAnti-A34.5 antibodyAnti-Antisense To Ercc-1 Protein antibodyAnti-Ase-1 antibodyAnti-Cd3-Epsilon-Associated Protein antibodyAnti-Cd3e-Associated Protein antibodyAnti-Dna-Directed Rna Polymerase I Subunit G antibodyAnti-Rna Polymerase I-Associated Factor Paf49 antibodyAnti-POLR1G antibodyAnti-ASE1 antibodyAnti-CAST antibodyAnti-CD3EAP antibodyAnti-PAF49 antibody |
Information sourced from Uniprot.org