Anti-CD38 antibody [PT0361R] (STJA0039539)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgGk
General Information
| Short Description | Rabbit monoclonal anti-Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 for use in WB, IHC, IF and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | PT0361R |
| Isotype | IgGk |
| Conjugation | Unconjugated |
| Purification | Protein A |
| Dilution Range | IHC 1:10000-1:30000WB 1:1000-1:5000IF 1:200-1:1000ELISA 1:5000-1:20000 |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CD38 |
| Gene ID | 952 |
| Uniprot ID | CD38_HUMAN |
| Specificity | Endogenous |
Additional Info
| Function | Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion. Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+). Has cADPR hydrolase activity. |
| Protein Name | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 12'-Phospho-Adp-Ribosyl Cyclase2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase2'-Phospho-Cyclic-Adp-Ribose TransferaseAdp-Ribosyl Cyclase 1Adprc 1Cyclic Adp-Ribose Hydrolase 1Cadpr Hydrolase 1T10Cd Antigen Cd38 |
| Database Links | Reactome: R-HSA-196807 |
| Cellular Localisation | Cell SurfaceMembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 antibodyAnti-2'-Phospho-Adp-Ribosyl Cyclase antibodyAnti-2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase antibodyAnti-2'-Phospho-Cyclic-Adp-Ribose Transferase antibodyAnti-Adp-Ribosyl Cyclase 1 antibodyAnti-Adprc 1 antibodyAnti-Cyclic Adp-Ribose Hydrolase 1 antibodyAnti-Cadpr Hydrolase 1 antibodyAnti-T10 antibodyAnti-Cd Antigen Cd38 antibodyAnti-CD38 antibody |
Information sourced from Uniprot.org