| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 is suitable for use in Flow Cytometry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | HIT2 |
| Conjugation: | PE/TR |
| Isotype: | IgG1k |
| Formulation: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Concentration: | 5 Mu L/Test |
| Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
| Gene Symbol: | CD38 |
| Gene ID: | 952 |
| Uniprot ID: | CD38_HUMAN |
| Tissue Specificity | Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. |
| Function | Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion. Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+). Has cADPR hydrolase activity. |
| Protein Name | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 2'-Phospho-Adp-Ribosyl Cyclase 2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase 2'-Phospho-Cyclic-Adp-Ribose Transferase Adp-Ribosyl Cyclase 1 Adprc 1 Cyclic Adp-Ribose Hydrolase 1 Cadpr Hydrolase 1 T10 Cd Antigen Cd38 |
| Database Links | Reactome: R-HSA-196807 |
| Cellular Localisation | Cell Surface Membrane Single-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 antibody Anti-2'-Phospho-Adp-Ribosyl Cyclase antibody Anti-2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase antibody Anti-2'-Phospho-Cyclic-Adp-Ribose Transferase antibody Anti-Adp-Ribosyl Cyclase 1 antibody Anti-Adprc 1 antibody Anti-Cyclic Adp-Ribose Hydrolase 1 antibody Anti-Cadpr Hydrolase 1 antibody Anti-T10 antibody Anti-Cd Antigen Cd38 antibody Anti-CD38 antibody |
Information sourced from Uniprot.org