Anti-CD370/CLEC9A nanobody [SAA1331] (STJN000327)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-C-Type Lectin Domain Family 9 Member A is suitable for use in ELISA and Flow Cytometry research applications. |
| Applications | ELISA/FC |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1331 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | CLEC9A |
| Gene ID | 283420 |
| Uniprot ID | CLC9A_HUMAN |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. |
| Protein Name | C-Type Lectin Domain Family 9 Member ACd Antigen Cd370 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Nanobody Names | Anti-C-Type Lectin Domain Family 9 Member A nanobodyAnti-Cd Antigen Cd370 nanobodyAnti-CLEC9A nanobodyAnti-UNQ9341 nanobodyAnti-PRO34046 nanobody |
Information sourced from Uniprot.org