Anti-CD370/CLEC9A antibody [R2CHCL10] (STJA0027284)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal C-Type Lectin Domain Family 9 Member A antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R2CHCL10 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/ml |
| Purification | Protein A/G purified from cell culture supernatant. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | CLEC9A |
| Gene ID | 283420 |
| Uniprot ID | CLC9A_HUMAN |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. |
| Protein Name | C-Type Lectin Domain Family 9 Member ACd Antigen Cd370 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-C-Type Lectin Domain Family 9 Member A antibodyAnti-Cd Antigen Cd370 antibodyAnti-CLEC9A antibodyAnti-UNQ9341 antibodyAnti-PRO34046 antibody |
Information sourced from Uniprot.org