Anti-CD370/CLEC9A antibody [R2CHCL10] {APC} (STJA0029739)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationAPC
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal C-Type Lectin Domain Family 9 Member A antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R2CHCL10 |
| Isotype | IgG1k |
| Conjugation | APC |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Formulation | PBS pH 7.4, 50% glycerol, 0.05% proclin300 |
| Storage Instruction | Store at 4°C for 12 months. Protect from light. Do not freeze. |
Target Information
| Gene Symbol | CLEC9A |
| Gene ID | 283420 |
| Uniprot ID | CLC9A_HUMAN |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. |
| Protein Name | C-Type Lectin Domain Family 9 Member ACd Antigen Cd370 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-C-Type Lectin Domain Family 9 Member A antibodyAnti-Cd Antigen Cd370 antibodyAnti-CLEC9A antibodyAnti-UNQ9341 antibodyAnti-PRO34046 antibody |
Information sourced from Uniprot.org