Anti-CD370/CLEC9A antibody {ABflo® 647} (STJ11108852)

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STJ11108852
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Short Description :Rabbit monoclonal CD370/CLEC9A antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Isotype:IgG
Conjugation:ABflo® 647
Purification:Affinity purification
Dilution Range:FC, 5 Mu l per 10^6 cells in 100 Mu l volume
Formulation:PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis) , pH 7.3.
Storage Instruction:Store at 4°C for up to 1 year from the date of receipt. Do not freeze.
Gene Symbol:CLEC9A
Gene ID:283420
Uniprot ID:CLC9A_HUMAN
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tissue Specificity In peripheral blood highly restricted on the surface of BDCA31(+) dendritic cells and on a small subset of CD14(+) and CD16(-) monocytes.
Post Translational Modifications N-glycosylated.
Function Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.
Protein Name C-Type Lectin Domain Family 9 Member A
Cd Antigen Cd370
Database Links
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-C-Type Lectin Domain Family 9 Member A antibody
Anti-Cd Antigen Cd370 antibody
Anti-CLEC9A antibody
Anti-UNQ9341 antibody
Anti-PRO34046 antibody

Information sourced from Uniprot.org

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