Anti-CD357/TNFRSF18/GITR antibody [SAA0100] (STJA0027272)
SPECIFICATIONS
ClonalityMonoclonal
HostHuman
ConjugationUnconjugated
IsotypeIgG1k
General Information
| Short Description | Human monoclonal Tumor Necrosis Factor Receptor Superfamily Member 18 antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Human |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0100 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/ml |
| Purification | Protein A/G purified from cell culture supernatant. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | TNFRSF18 |
| Gene ID | 8784 |
| Uniprot ID | TNR18_HUMAN |
Additional Info
| Function | Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 18Activation-Inducible Tnfr Family ReceptorGlucocorticoid-Induced Tnfr-Related ProteinCd Antigen Cd357 |
| Database Links | Reactome: R-HSA-5669034Reactome: R-HSA-8877330 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 18 antibodyAnti-Activation-Inducible Tnfr Family Receptor antibodyAnti-Glucocorticoid-Induced Tnfr-Related Protein antibodyAnti-Cd Antigen Cd357 antibodyAnti-TNFRSF18 antibodyAnti-AITR antibodyAnti-GITR antibodyAnti-UNQ319 antibodyAnti-PRO364 antibody |
Information sourced from Uniprot.org