Anti-CD35 antibody [E11] (STJ16101912)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenHuman acute monocytic leukaemia cells
General Information
| Short Description | Mouse monoclonal anti-CD35 for use in IHC-F, FC, IHC-P and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-F/FC/IHC-P/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | E11 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Formulation | PBS with <0.1% sodium azide |
| Storage Instruction | Store aliquots at-20°C, and thawed aliquots at 2-8°C. |
Target Information
| Immunogen | Human acute monocytic leukaemia cells |
Additional Info
| Background | Mouse anti Human CD35 antibody, clone E11 recognizes complement receptor type 1, also known as CD35 or the C3b/C4b receptor. CD35 a single chain, type I single pass transmembrane glycoprotein which exists in four allotypic forms (A, B, C, D) of ~190 kDa, ~220 kDa, ~160 kDa and ~250 kDa respectively (Khera et al. 2009).CD35 is expressed by granulocytes, monocytes, B cells and some T cells. Functionally, CD35 acts as a receptor for the C3b component of complement. |
Information sourced from Uniprot.org