Anti-CD34 antibody [SQab1870] (STJ16102883)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
ImmunogenSynthetic peptide around the C-terminus of CD34.
General Information
| Short Description | Rabbit monoclonal anti-CD34 for use in FC and IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SQab1870 |
| Conjugation | Unconjugated |
| Purification | Purification with Protein A. |
| Formulation | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| Storage Instruction | Store at-20°C for up to 1 year. Minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | CD34 |
| Gene ID | 947 |
| Uniprot ID | CD34_HUMAN |
| Immunogen | Synthetic peptide around the C-terminus of CD34. |
Additional Info
| Post Translational Modifications | Highly glycosylated. Phosphorylated on serine residues by PKC. |
| Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
| Protein Name | Hematopoietic Progenitor Cell Antigen Cd34Cd Antigen Cd34 |
| Database Links | Reactome: R-HSA-198933 P28906-1 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Hematopoietic Progenitor Cell Antigen Cd34 antibodyAnti-Cd Antigen Cd34 antibodyAnti-CD34 antibody |
Information sourced from Uniprot.org