| Short Description : | Mouse monoclonal CD34 antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-P |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | QBEnd‐10 |
| Isotype: | IgG1/L2 |
| Conjugation: | Unconjugated |
| Purification: | Affinity purified |
| Dilution Range: | 1:100‐200 |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | CD34 |
| Gene ID: | 947 |
| Uniprot ID: | CD34_HUMAN |
| Immunogen: | Detergent solubilized vesicular suspension prepared from a perfusate of human term placenta |
| Specificity: | Positive control: Hemangioma |
| Tissue Specificity | Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. |
| Post Translational Modifications | Highly glycosylated. Phosphorylated on serine residues by PKC. |
| Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
| Protein Name | Hematopoietic Progenitor Cell Antigen Cd34Cd Antigen Cd34 |
| Database Links | Reactome: R-HSA-198933 P28906-1 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Hematopoietic Progenitor Cell Antigen Cd34 antibodyAnti-Cd Antigen Cd34 antibodyAnti-CD34 antibody |
Information sourced from Uniprot.org
![Anti-CD34 antibody [QBEnd/10] (STJ16101737)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/152243/347093/STJ16101737_1__78694.1681999357.jpg?c=1 "Anti-CD34 antibody [QBEnd/10] (STJ16101737)")
