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![Anti-CD34 antibody [QBEnd/10] (STJ16101737)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/152243/347093/STJ16101737_1__78694.1681999357.jpg?c=1 "Anti-CD34 antibody [QBEnd/10] (STJ16101737)")
Anti-CD34 antibody [QBEnd/10] (STJ16101737)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenDetergent solubilized vesicular suspension prepared from a perfusate of human term placenta.
General Information
| Short Description | Mouse monoclonal anti-CD34 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | QBEnd/10 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | >=261 mg/L |
| Dilution Range | IHC-P 1:100 |
| Formulation | Tissue culture supernatant with Sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | CD34 |
| Gene ID | 947 |
| Uniprot ID | CD34_HUMAN |
| Immunogen | Detergent solubilized vesicular suspension prepared from a perfusate of human term placenta. |
Additional Info
| Tissue Specificity | Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. |
| Post Translational Modifications | Highly glycosylated. Phosphorylated on serine residues by PKC. |
| Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
| Protein Name | Hematopoietic Progenitor Cell Antigen Cd34Cd Antigen Cd34 |
| Database Links | Reactome: R-HSA-198933 P28906-1 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Hematopoietic Progenitor Cell Antigen Cd34 antibodyAnti-Cd Antigen Cd34 antibodyAnti-CD34 antibody |
Information sourced from Uniprot.org