Anti-CD34 antibody [QBEND-10] (STJ16100095)

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STJ16100095-02
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Host: Mouse
Applications: IHC-F/IHC-P/WB/FC/IP/IF/EM
Reactivity: Human/Rhesus/Cynomolgus Monkey
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-CD34 for use in IHC-F, IHC-P, WB, FC, IP, IF and EM in Human, Rhesus and Cynomolgus Monkey samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : QBEND-10
Conjugation: Unconjugated
Isotype: IgG1
Formulation: PBS with 0.09% sodium azide
Concentration: 1.0 mg/mL
Dilution Range: FC 1:100-1:200
IHC 1:500-1:1000
Storage Instruction: Store at 2-8°C for up to 1-year, upon receipt.
Gene Symbol: CD34
Gene ID: 947
Uniprot ID: CD34_HUMAN
Immunogen: Human endothelial cell membrane vesicles.
Tissue Specificity Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
Post Translational Modifications Highly glycosylated. Phosphorylated on serine residues by PKC.
Function Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
Protein Name Hematopoietic Progenitor Cell Antigen Cd34
Cd Antigen Cd34
Database Links Reactome: R-HSA-198933 P28906-1
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Hematopoietic Progenitor Cell Antigen Cd34 antibody
Anti-Cd Antigen Cd34 antibody
Anti-CD34 antibody

Information sourced from Uniprot.org

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