Anti-CD34 antibody [MEC14.7] (STJ16100091)
SPECIFICATIONS
ClonalityMonoclonal
HostRat
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Rat monoclonal anti-CD34 for use in IHC-F, IHC-P, FC, IF, IP and WB in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-F/IHC-P/FC/IF/IP/WB |
| Host | Rat |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | MEC14.7 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 100 Mu g/mL |
| Dilution Range | IHC-F 1:50IF 1:50FC 1:50 |
| Formulation | PBS with 0.1% BSA and 0.02% sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | CD34 |
| Gene ID | 947 |
| Uniprot ID | CD34_HUMAN |
Additional Info
| Tissue Specificity | Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. |
| Post Translational Modifications | Highly glycosylated. Phosphorylated on serine residues by PKC. |
| Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
| Protein Name | Hematopoietic Progenitor Cell Antigen Cd34Cd Antigen Cd34 |
| Database Links | Reactome: R-HSA-198933 P28906-1 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Hematopoietic Progenitor Cell Antigen Cd34 antibodyAnti-Cd Antigen Cd34 antibodyAnti-CD34 antibody |
Information sourced from Uniprot.org