Anti-CD34 antibody [581] {R-PE} (STJA0018309)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationR-PE
IsotypeIgG1
STJA0018309-5
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General Information

Short DescriptionMouse monoclonal anti-Hematopoietic Progenitor Cell antigen Cd34 for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsFC
HostMouse
ReactivityHuman
NoteFOR RESEARCH USE ONLY (RUO).

Product Properties

ClonalityMonoclonal
Clone ID581
IsotypeIgG1
ConjugationR-PE
PurificationProtein A purification
Dilution RangePlease carry out application specific titration to determine the most appropriate dilution ratio.
FormulationPBS with 0.2% BSA, and 0.09% Sodium Azide
Storage InstructionShipped on gel ice packs. Store at 2-8C on arrival.

Target Information

Gene SymbolCD34
Gene ID947
Uniprot IDCD34_HUMAN

Additional Info

Post Translational Modifications Highly glycosylated. Phosphorylated on serine residues by PKC.
Function Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
Protein Name Hematopoietic Progenitor Cell Antigen Cd34
Cd Antigen Cd34
Database Links Reactome: R-HSA-198933 P28906-1
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Hematopoietic Progenitor Cell Antigen Cd34 antibody
Anti-Cd Antigen Cd34 antibody
Anti-CD34 antibody

Information sourced from Uniprot.org

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