Anti-CD335/NKp46 antibody {ABflo® 647} (STJ11108703)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationABflo® 647
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal CD335/NKp46 antibody for use in IF, ICC and FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/ICC/FC |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | ABflo® 647 |
| Purification | Affinity purification |
| Dilution Range | IF/ICC, 1:50-1:200|FC, 5 Mu l per 10^6 cells in 100 Mu l volume |
| Formulation | PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis) , pH 7.3. |
| Storage Instruction | Store at 4°C for up to 1 year from the date of receipt. Do not freeze. |
Target Information
| Gene Symbol | NCR1 |
| Gene ID | 9437 |
| Uniprot ID | NCTR1_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Tissue Specificity | Selectively expressed by both resting and activated NK cells. |
| Post Translational Modifications | N-glycosylated. O-glycosylated. |
| Function | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. |
| Protein Name | Natural Cytotoxicity Triggering Receptor 1Lymphocyte Antigen 94 HomologNk Cell-Activating ReceptorNatural Killer Cell P46-Related ProteinNk-P46Nkp46Hnkp46Cd Antigen Cd335 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Natural Cytotoxicity Triggering Receptor 1 antibodyAnti-Lymphocyte Antigen 94 Homolog antibodyAnti-Nk Cell-Activating Receptor antibodyAnti-Natural Killer Cell P46-Related Protein antibodyAnti-Nk-P46 antibodyAnti-Nkp46 antibodyAnti-Hnkp46 antibodyAnti-Cd Antigen Cd335 antibodyAnti-NCR1 antibodyAnti-LY94 antibody |
Information sourced from Uniprot.org