Anti-CD326/EPCAM antibody [MT201] {FITC} (STJA0028253)
SPECIFICATIONS
ClonalityMonoclonal
HostHuman
ConjugationFITC
IsotypeIgG1
General Information
| Short Description | Human monoclonal Epithelial Cell Adhesion Molecule antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Human |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | MT201 |
| Isotype | IgG1 |
| Conjugation | FITC |
| Concentration | 05 mg/mL |
| Purification | Purified |
| Formulation | PBS pH 7.4, 50% glycerol, 0.05% proclin300 |
| Storage Instruction | Store at 4°C for 12 months Protect from light Do not freeze |
Target Information
| Gene Symbol | EPCAM |
| Gene ID | 4072 |
| Uniprot ID | EPCAM_HUMAN |
Additional Info
| Post Translational Modifications | Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability. |
| Function | May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. |
| Protein Name | Epithelial Cell Adhesion MoleculeEp-CamAdenocarcinoma-Associated AntigenCell Surface Glycoprotein Trop-1Epithelial Cell Surface AntigenEpithelial GlycoproteinEgpEpithelial Glycoprotein 314Egp314Hegp314Ks 1/4 AntigenKsaMajor Gastrointestinal Tumor-Associated Protein Ga733-2Tumor-Associated Calcium Signal Transducer 1Cd Antigen Cd326 |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Lateral Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionTight JunctionColocalizes With Cldn7 At The Lateral Cell Membrane And Tight Junction |
| Alternative Antibody Names | Anti-Epithelial Cell Adhesion Molecule antibodyAnti-Ep-Cam antibodyAnti-Adenocarcinoma-Associated Antigen antibodyAnti-Cell Surface Glycoprotein Trop-1 antibodyAnti-Epithelial Cell Surface Antigen antibodyAnti-Epithelial Glycoprotein antibodyAnti-Egp antibodyAnti-Epithelial Glycoprotein 314 antibodyAnti-Egp314 antibodyAnti-Hegp314 antibodyAnti-Ks 1/4 Antigen antibodyAnti-Ksa antibodyAnti-Major Gastrointestinal Tumor-Associated Protein Ga733-2 antibodyAnti-Tumor-Associated Calcium Signal Transducer 1 antibodyAnti-Cd Antigen Cd326 antibodyAnti-EPCAM antibodyAnti-GA733-2 antibodyAnti-M1S2 antibodyAnti-M4S1 antibodyAnti-MIC18 antibodyAnti-TACSTD1 antibodyAnti-TROP1 antibody |
Information sourced from Uniprot.org