Anti-CD32/FcgR2 nanobody [SAA2150] (STJN000613)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A is suitable for use in Universaling and ELISA research applications. |
| Applications | Blocking/ELISA |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA2150 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | FCGR2A |
| Gene ID | 2212 |
| Uniprot ID | FCG2A_HUMAN |
Additional Info
| Post Translational Modifications | Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK. |
| Function | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. |
| Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-AIgg Fc Receptor Ii-ACdw32Fc-Gamma Rii-AFc-Gamma-RiiaFcrii-ACd Antigen Cd32 |
| Database Links | Reactome: R-HSA-2029481Reactome: R-HSA-2029482Reactome: R-HSA-2029485Reactome: R-HSA-6798695Reactome: R-HSA-9664323 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Nanobody Names | Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A nanobodyAnti-Igg Fc Receptor Ii-A nanobodyAnti-Cdw32 nanobodyAnti-Fc-Gamma Rii-A nanobodyAnti-Fc-Gamma-Riia nanobodyAnti-Fcrii-A nanobodyAnti-Cd Antigen Cd32 nanobodyAnti-FCGR2A nanobodyAnti-CD32 nanobodyAnti-FCG2 nanobodyAnti-FCGR2A1 nanobodyAnti-IGFR2 nanobody |
Information sourced from Uniprot.org