Anti-CD303/CLEC4C antibody [122A2] (STJA0027234)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal C-Type Lectin Domain Family 4 Member C antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 122A2 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/ml |
| Purification | Protein A/G purified from cell culture supernatant. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | CLEC4C |
| Gene ID | 170482 |
| Uniprot ID | CLC4C_HUMAN |
Additional Info
| Function | Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. |
| Protein Name | C-Type Lectin Domain Family 4 Member CBlood Dendritic Cell Antigen 2Bdca-2C-Type Lectin Superfamily Member 7Dendritic LectinCd Antigen Cd303 |
| Database Links | Reactome: R-HSA-5621480Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-C-Type Lectin Domain Family 4 Member C antibodyAnti-Blood Dendritic Cell Antigen 2 antibodyAnti-Bdca-2 antibodyAnti-C-Type Lectin Superfamily Member 7 antibodyAnti-Dendritic Lectin antibodyAnti-Cd Antigen Cd303 antibodyAnti-CLEC4C antibodyAnti-BDCA2 antibodyAnti-CLECSF11 antibodyAnti-CLECSF7 antibodyAnti-DLEC antibodyAnti-HECL antibodyAnti-UNQ9361 antibodyAnti-PRO34150 antibody |
Information sourced from Uniprot.org