![Anti-CD300 antibody [MEM-260] (STJ16100827)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149544/346875/STJ16100827_1__22452.1681999035.jpg?c=1 "Anti-CD300 antibody [MEM-260] (STJ16100827)")
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| Short Description : | Mouse monoclonal anti-CD300 for use in FC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | FC/WB |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | MEM-260 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Formulation: | Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Storage Instruction: | Store at 2-8°C for up to 1-year, upon receipt. |
| Immunogen: | HPB human acute lymphoid leukemia cell line |
| Background | CD300a (CMRF-35H, IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily, which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells, NK cells, neutrophils, eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5, GM-CSF or eotaxin, as well as supresses mast cell degranulation or NK cell cytotoxic activity. |
Information sourced from Uniprot.org
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