Anti-CD30 antibody [ZN256] (STJA0033402)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenHuman recombinant protein fragment of human TNFRSF8 (NP_001234) produced in E.coli.
STJA0033402
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General Information

Short DescriptionMouse monoclonal anti-CD30 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC-P
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDZN256
IsotypeIgG1
ConjugationUnconjugated
Concentration0.5-1.0 mg/mL
PurificationAffinity Chromatography
Dilution RangeIHC 1:50-1:100
FormulationPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage InstructionStore at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.

Target Information

Gene SymbolTNFRSF8
Gene ID943
Uniprot IDTNR8_HUMAN
ImmunogenHuman recombinant protein fragment of human TNFRSF8 (NP_001234) produced in E.coli.

Additional Info

Tissue Specificity Isoform 2: Detected in alveolar macrophages (at protein level).
Post Translational Modifications Phosphorylated on serine and tyrosine residues (Probable). Isoform 2 is constitutively phosphorylated.
Function Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 8
Cd30l Receptor
Ki-1 Antigen
Lymphocyte Activation Antigen Cd30
Cd Antigen Cd30
Database Links Reactome: R-HSA-5669034
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Cytoplasm
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 8 antibody
Anti-Cd30l Receptor antibody
Anti-Ki-1 Antigen antibody
Anti-Lymphocyte Activation Antigen Cd30 antibody
Anti-Cd Antigen Cd30 antibody
Anti-TNFRSF8 antibody
Anti-CD30 antibody
Anti-D1S166E antibody

Information sourced from Uniprot.org

Citations

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