Anti-CD30 antibody (Full length) [ZR248] (STJ180494)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant human full-length TNFRSF8 protein (CD30)
General Information
| Short Description | Rabbit monoclonal CD30 (Full length) antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZR248 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purified |
| Dilution Range | 1:100-200 |
| Formulation | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Target Information
| Gene Symbol | TNFRSF8 |
| Gene ID | 943 |
| Uniprot ID | TNR8_HUMAN |
| Immunogen | Recombinant human full-length TNFRSF8 protein (CD30) |
| Immunogen Region | Full length |
| Specificity | Positive control: Hodgkin lymphoma or anaplastic large cell lymphoma |
Additional Info
| Tissue Specificity | Isoform 2: Detected in alveolar macrophages (at protein level). |
| Post Translational Modifications | Phosphorylated on serine and tyrosine residues (Probable). Isoform 2 is constitutively phosphorylated. |
| Function | Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 8Cd30l ReceptorKi-1 AntigenLymphocyte Activation Antigen Cd30Cd Antigen Cd30 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 8 antibodyAnti-Cd30l Receptor antibodyAnti-Ki-1 Antigen antibodyAnti-Lymphocyte Activation Antigen Cd30 antibodyAnti-Cd Antigen Cd30 antibodyAnti-TNFRSF8 antibodyAnti-CD30 antibodyAnti-D1S166E antibody |
Information sourced from Uniprot.org