Anti-CD298/ATP1B3 antibody (180-279 aa) [SRM5039] (STJ11106584)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal CD298/ATP1B3 (180-279 aa) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM5039 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1500-1:3000IHC-P:1:100-1:500IF/ICC:1:200-1:800ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
Target Information
| Gene Symbol | ATP1B3 |
| Gene ID | 483 |
| Uniprot ID | AT1B3_HUMAN |
| Immunogen Region | 180-279 aa |
| Immunogen Sequence | GLKPEGVPRIDCVSKNEDIP NVAVYPHNGMIDLKYFPYYG KKLHVGYLQPLVAVQVSFAP NNTGKEVTVECKIDGSANLK SQDDRDKFLGRVMFKITARA |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 180-279 of human ATP1B3 (P54709). |
Additional Info
| Function | This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known. |
| Protein Name | Sodium/Potassium-Transporting Atpase Subunit Beta-3Sodium/Potassium-Dependent Atpase Subunit Beta-3Atpb-3Cd Antigen Cd298 |
| Database Links | Reactome: R-HSA-210991Reactome: R-HSA-5578775Reactome: R-HSA-936837Reactome: R-HSA-9679191 |
| Cellular Localisation | Apical Cell MembraneSingle-Pass Type Ii Membrane ProteinBasolateral Cell MembraneMelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Sodium/Potassium-Transporting Atpase Subunit Beta-3 antibodyAnti-Sodium/Potassium-Dependent Atpase Subunit Beta-3 antibodyAnti-Atpb-3 antibodyAnti-Cd Antigen Cd298 antibodyAnti-ATP1B3 antibody |
Information sourced from Uniprot.org