Anti-CD28 antibody [204.12] (STJ16100044)

SKU:
STJ16100044-100

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Host: Mouse
Applications: FC/IHC-F/IF
Reactivity: Human/Mouse/Pig/Sheep/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CD28 is suitable for use in Flow Cytometry, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: 204.12
Conjugation: Unconjugated
Isotype: IgG2b
Formulation: PBS with 0.02% sodium azide
Concentration: 100 ug/mL
Dilution Range: FC 0
5-1
0 µg/million cells in 0
1 ml-IF 0
5-1
0 µg/ml-IHC frozen 1-2 µg/ml for 30-60 min at RT
Storage Instruction: Store at 2-8°C upon receipt.
Gene Symbol: CD28
Gene ID: 940
Uniprot ID: CD28_HUMAN
Immunogen: Stimulated human leucocytes
Tissue Specificity Expressed in T-cells and plasma cells, but not in less mature B-cells.
Post Translational Modifications CD40LG induces tyrosine phosphorylation of isoform 3.
Function Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells.
Protein Name T-Cell-Specific Surface Glycoprotein Cd28
Tp44
Cd Antigen Cd28
Database Links Reactome: R-HSA-1257604
Reactome: R-HSA-164939
Reactome: R-HSA-2219530
Reactome: R-HSA-389356
Reactome: R-HSA-389357
Reactome: R-HSA-389359
Reactome: R-HSA-6811558
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Isoform 3: Cell Surface
Alternative Antibody Names Anti-T-Cell-Specific Surface Glycoprotein Cd28 antibody
Anti-Tp44 antibody
Anti-Cd Antigen Cd28 antibody
Anti-CD28 antibody

Information sourced from Uniprot.org

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