Host: |
Mouse |
Applications: |
FC |
Reactivity: |
Human |
Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-Programmed cell death 1 ligand 2 is suitable for use in Flow Cytometry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
24F.10C12 |
Conjugation: |
APC |
Isotype: |
IgG2ak |
Formulation: |
PBS with 0.05% Proclin300, 1% BSA |
Storage Instruction: |
Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
Tissue Specificity | Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. |
Function | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
Protein Name | Programmed Cell Death 1 Ligand 2Pd-1 Ligand 2Pd-L2Pdcd1 Ligand 2Programmed Death Ligand 2Butyrophilin B7-DcB7-DcCd Antigen Cd273 |
Database Links | Reactome: R-HSA-389948 |
Cellular Localisation | Isoform 3: SecretedIsoform 2: Endomembrane SystemSingle-Pass Type I Membrane ProteinIsoform 1: Cell Membrane |
Alternative Antibody Names | Anti-Programmed Cell Death 1 Ligand 2 antibodyAnti-Pd-1 Ligand 2 antibodyAnti-Pd-L2 antibodyAnti-Pdcd1 Ligand 2 antibodyAnti-Programmed Death Ligand 2 antibodyAnti-Butyrophilin B7-Dc antibodyAnti-B7-Dc antibodyAnti-Cd Antigen Cd273 antibodyAnti-PDCD1LG2 antibodyAnti-B7DC antibodyAnti-CD273 antibodyAnti-PDCD1L2 antibodyAnti-PDL2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance