Anti-CD25 antibody [IHC025] (STJA0042112)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
General Information
| Short Description | Rabbit monoclonal anti-CD25 for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-p |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | IHC025 |
| Conjugation | Unconjugated |
| Formulation | Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1 year. Do not freeze. |
Target Information
| Specificity | Tested and validated on lesions of mastocytosis tissue. |
Additional Info
| Background | Cluster of Differentiation 25 (CD25) is the extracellular region of the interleukin-2 receptor on activated B-and T-cells, myeloid precursors, and some other types of leukocytes. Since CD25 staining is useful for differentiating neoplastic mast cell aggregates from reactive proliferations, Anti-CD25 has become a major criterion for Systemic Mastocytosis diagnoses. In the context of urticaria pigmentosa, CD25 staining is also used to recognize mast cells in skin biopsies. There is a greater proportion of CD25+ and FOXP3+ regulatory T-cells among cancer cells in tumour parenchyma and its periphery in recurrent cutaneous melanoma compared to non-recurrent melanoma. |
Information sourced from Uniprot.org